Objective To investigate the effect of recombined osteogenic growth peptide ( ROGP) on tissue engineers osteo-myocutaneohs flaps. 目的探讨重组骨生长肽对组织工程性骨肌皮瓣的影响。
The results obtained from this study provide important informations for future development of osteogenic tissue scaffolds. 综合以上本研究所得的结果,可提供了一些资讯对于未来骨组织支架的进一步发展。
Osteogenic Induction of Bone Marrow-derived Mesenchymal Stem Cells within Strain for Tissue Engineering 组织工程中应力对骨髓间充质干细胞分化为成骨细胞的影响
Results Both X ray and tissue slicing showed that woven, trabecular and laminar bones were formed throughout the whole defected areas during different stages of restoration in the experimental group while osteogenic tissue only appeared in the margin of ceramic in the control group. 结果无论X线摄片及组织切片均表明,实验组颅骨极量缺损修复优于同期对照组。
Objective: To study the osteogenic methods and abilities of the dog's bone marrow stromal cells ( BMSCs) in vitro to estimate its feasibility of being seed cells of bone tissue engineering. 目的:研究犬骨髓基质细胞(BoneMarrowStromalcells,BMSCs)在体外诱导分化为成骨细胞的方法和活性检测。
However, no bone formation could be found in the β-TCP scaffolds without the cells at each time point checked, Conclusion Novel β-TCP scaffolds prepared by the polymeric sponge method have excellent osteogenic potentials and can be used as biomaterials for bone tissue engineering. 单纯材料组在各时间点均未成骨。结论有机泡沫浸渍法制备的多孔β-TCP生物陶瓷具有良好的支持成骨能力,是一种较理想的骨组织工程支架材料。
Objective To explore the osteogenic potential of cultured fetal dermal papilla cells in vitro and provide a new ideal seeded cells for bone tissue engineering. 目的研究胎儿毛乳头细胞的体外成骨能力,为骨组织工程提供一种新的种子细胞。
Conclusion HAB loaded with induced BMSCs has an excellent osteogenic function in vitro and presents an effective potential to be a good bone tissue engineering material. 结论人脱细胞骨复合经诱导的骨髓基质细胞在体外具有有效的成骨功能,是一种较为理想的骨组织工程材料。
No osteogenic tissue was found within the tumor. Conclusion Spiral CT scans can precisely reflect the pathologic features of NOF. 结论螺旋CT能够细致、准确地反映非骨化性纤维瘤的病理学特征。
Conclusion: BMSCs after osteogenic stimulation show the phenotype characteristics of osteoblast, and can be used for the seed cells of tissue engineering of bone. 结论:体外成骨定向诱导的BMSCs具有典型的成骨细胞的形态和功能性特征,可以作为骨组织工程的种子细胞。
Conclusion: The MSCs obtained in our experiment have a strong activity of proliferation and osteogenic potentiality. This study reveals that the MSCs can be used as the seed cells in the bone tissue engineering. 结论:狗骨髓基质细胞在本实验条件下,成骨能力肯定,增殖能力强,可作为骨组织工程的种子细胞。
Conclusion Adipose-derived stem cells can be isolated from rat adipose tissue. Their biological characteristics are similar with mesenchymal stem cells ( MSCs), and have the potential to differentiate into osteogenic and chondrogenic lineage. It may be an idea source of ADSCs for tissue engineering. 结论大鼠脂肪组织可以分离培养出ADSCs,生物学特性与骨髓基质干细胞(MesenchymalStemcells,MSCs)相似,能够向成骨细胞、软骨细胞分化,有希望成为组织工程理想的种子细胞来源。
The volume density was significantly different between the osteogenic tissue and inflammatory tissue ( P < 0.01), indicating that there were more new bone formation and milder inflammatory reactions in the gentamicin treatment group than in the control group. 成骨组织及炎性组织体积密度上差异均存在统计学意义(P<0.01),说明实验组比对照组有较多的新骨形成与较轻微的炎性反应。
Adult human blood-derived MSCs possess osteogenic potential in vitro, and may be used as seed cells for bone tissue engineering. 成人血源性MSCs具有较强的体外成骨潜能,可望成为一种新的骨组织工程种子细胞。
Objective: To observe the morphological changes and phenotype characteristics of bone marrow stromal stem cells ( BMSCs) during osteogenic inducement and to identify the feasibility as the seed cells for tissue engineering of bone. 目的:研究大鼠骨髓基质干细胞(BMSCs)在体外培养、诱导后的形态学改变及生物活性,探讨BMSCs作为骨组织工程种子细胞的可能性和可行性。
Objective To study the biocompatibility and osteogenic activity of allogenic decalcified bone matrix ( DBM) used as a carrier for bone tissue engineering by bone marrow stromal cells ( BMSC) and DBM co-culture in vitro and ectopic bone formation in vivo. 目的通过体外同种异体脱钙骨基质(DBM)和骨髓基质细胞(BMSC)的复合培养及体内异位成骨实验,研究DBM作为骨组织工程载体的生物相容性及成骨活性。
Objective To explore the osteogenic action of biological derivative bone as scaffolds of tissue engineering bone combined with osteoblast cultured in vitro and its applicability to act as scaffold materials of tissue engineering. 目的:探讨生物衍生骨作为组织工程骨支架复合成骨细胞体内植入的成骨作用,了解其用于骨组织工程支架材料的可行性。
Objective: To observe the phenotype characteristics of mesenchymal stem cells ( MSCs) during osteogenic stimulation and to identify the feasibility as the seed cells for tissue engineering of bone. 目的:探讨体外成骨诱导的兔骨髓间质干细胞(MSCs)的形态和功能特征,以及其作为骨组织工程种子细胞的可行性。
Thus we confirm the osteogenic capability of ADASCs in vivo and provide the important evidence of applying ADASCs in bone tissue engineering extensively as seed cell. 这样就肯定和明确了ADASCs在体内的成骨能力,从而为ADASCs作为种子细胞在骨组织工程中的广泛应用提供了坚实的理论依据。
( 8) New bone formation of the co-culture cell group was the largest, vascular endothelial cells can enhance the osteogenic potential of the tissue engineering. 联合培养细胞组修复骨缺损能力最强,血管内皮细胞能增强组织工程骨成骨能力。
( 6) New bone formation of the co-culture cell group was the largest, vascular endothelial cells can enhance the osteogenic potential of the tissue engineering; Each tissue engineering bones adhered Cells can not caused severe immune rejection in vivo. 联合培养细胞组异位成骨能力最强,血管内皮细胞能增强组织工程骨成骨能力;各复合细胞组织工程骨机体内未引起明显免疫排斥反应。
The studies found that EPCs can osteogenic differentiation, and enhance the ability of self-healing and the formation of blood vessels in ischemic tissue through paracrine potential for treatment of ANFH. 研究发现EPCs具有可以向成骨方向分化,通过旁分泌作用增强缺血组织自我修复和形成血管的能力,有用于治疗ANFH的潜力。
Tissue engineering bone is expected to solve the problem that new bone grows slowly after transplant. How to accelerate the proliferation of seeded cells and promote the osteogenic differentiation has become a key problem as well as a research focus in tissue engineering. 组织工程骨有望解决植骨后新骨形成缓慢的问题,其中如何促进种子细胞的增殖和成骨分化成为组织工程技术的关键环节和研究热点。